STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPCC23B6.02cShuttling pre-60S factor C23B6.02c; Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus. (111 aa)    
Predicted Functional Partners:
nop16
Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit.
   
 
  0.809
rlp7
60S ribosomal protein L7-A.
   
 
  0.755
nsa2
Ribosome biogenesis protein nsa2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
   
 
  0.754
noc201
Uncharacterized NOC2 family protein C1142.04.
   
 
  0.736
noc1
Uncharacterized protein C4F10.09c; Belongs to the CBF/MAK21 family.
   
 
  0.734
skb15
Shk1 kinase-binding protein 15; Negatively regulates pak1/shk1 kinase activity leading to proper execution of cytoskeletal remodeling and cytokinetic functions.
   
  
 0.734
rlp24
Ribosome biogenesis protein rlp24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase afg2 to cytoplasmic pre-60S ribosomal particles.
   
 
  0.728
sdo1
Ribosome maturation protein sdo1; Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with the EF-2-like GTPase ria1, may trigger the GTP-dependent release of tif6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating tif6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.
   
 
  0.727
noc3
Nucleolar complex-associated protein 3; May be required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.
   
 
  0.726
mdn1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus.
   
 
  0.722
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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