STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPX_ENCCUProbable phospholipid hydroperoxide glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione; Belongs to the glutathione peroxidase family. (177 aa)    
Predicted Functional Partners:
Q8SQV7_ENCCU
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.954
Q8SSF2_ENCCU
THIOREDOXIN REDUCTASE.
  
  
 0.866
TDX_ENCCU
Putative thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
  
 
 0.834
Q8SVY0_ENCCU
Uncharacterized protein.
   
 0.701
Q8SWK5_ENCCU
Similarity to THIOREDOXIN H type.
  
 0.700
Q8SQL1_ENCCU
PROTEIN DISULFIDE ISOMERASE.
  
 0.629
Q8SRV2_ENCCU
GAMMA GLUTAMYL TRANSPEPTIDASE.
     
 0.622
Q8SRJ8_ENCCU
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.602
Q8SQL7_ENCCU
THIOLTRANSFERASE (GLUTAREDOXIN).
  
 
 0.586
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
     
 0.577
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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