STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLO2_ENCCUProbable hydroxyacylglutathione hydrolase ECU02_0580; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (249 aa)    
Predicted Functional Partners:
NFS1
Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.724
Q8SRL4_ENCCU
Putative EXONUCLEASE.
     
 0.686
ISU1
Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]
  
 
  0.642
Q8SRE9_ENCCU
DNA-DIRECTED RNA POLYMERASE I.
   
  
 0.606
Q8SQZ1_ENCCU
Triosephosphate isomerase.
  
 
 0.590
GPX_ENCCU
Probable phospholipid hydroperoxide glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione; Belongs to the glutathione peroxidase family.
  
  
 0.570
ALDR_ENCCU
Aldose reductase; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
  
  
 0.556
Q8SWD1_ENCCU
Uncharacterized protein.
  
  
 0.543
Q8SVD6_ENCCU
Lactamase_B domain-containing protein.
     
 0.519
RPE1
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.513
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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