STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IMPO_ENCCUProbable importin ECU10_0620; Active in protein import into the nucleus. (939 aa)    
Predicted Functional Partners:
GSP1
GTP-binding nuclear protein GSP1; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export (By similarity); Belongs to the small GTPase superfamily. Ran family.
   
 0.892
Q8SR21_ENCCU
IMPORTIN BETA 1 SUBUNIT (KARYOPHERIN).
   
 
 0.838
Q8SU35_ENCCU
HRDC domain-containing protein.
   
 0.781
Q8SRR8_ENCCU
NUCLEAR PORE COMPLEX PROTEIN NUP155.
   
 0.739
Q8SW87_ENCCU
Uncharacterized protein.
   
 0.732
Q8SUC4_ENCCU
KH_dom_type_1 domain-containing protein.
   
 0.711
RPB2
DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...]
   
 
 0.702
YRB1
Ran-specific GTPase-activating protein 1; Important for the export of protein containing nuclear export signal (NES) out of the nucleus.
   
 0.695
Q8SU48_ENCCU
Uncharacterized protein.
   
 0.670
Q8STQ1_ENCCU
KH_dom_type_1 domain-containing protein.
   
 0.667
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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