STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMPL_ENCCUCytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). (486 aa)    
Predicted Functional Partners:
Q8SRV2_ENCCU
GAMMA GLUTAMYL TRANSPEPTIDASE.
  
 
 0.958
SHMT-1
Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.876
Q8SS55_ENCCU
AMINOPEPTIDASE P-LIKE PROTEIN; Belongs to the peptidase M24B family.
  
 
 0.823
MAP2
Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
  
  
 0.798
Q8SSF2_ENCCU
THIOREDOXIN REDUCTASE.
  
  
 0.798
Q8SSG0_ENCCU
Signal peptidase complex catalytic subunit SEC11.
  
  
 0.700
NFS1
Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.670
CDC5
Probable cell cycle serine/threonine-protein kinase CDC5 homolog; Protein kinase required for the cell cycle where it is involved in mitotic exit. Required to form a bipolar spindle, the actin ring and septum. Functions upstream of the whole septum formation pathway, including actin ring formation (regulated by late septation genes) and septal material deposition (regulated by early septation genes). Behaves as a 'septum-promoting factor', and could also be involved in inducing other late events of cell division (By similarity).
    
 0.626
Q8SWD1_ENCCU
Uncharacterized protein.
     
 0.621
Q8SRQ2_ENCCU
UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; Belongs to the peptidase C19 family.
    
 0.607
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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