STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUB4Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity). (434 aa)    
Predicted Functional Partners:
Q8SU99_ENCCU
Spindle pole body component.
   
 0.999
Q8SVK3_ENCCU
Spindle pole body component.
   
 0.999
CDC5
Probable cell cycle serine/threonine-protein kinase CDC5 homolog; Protein kinase required for the cell cycle where it is involved in mitotic exit. Required to form a bipolar spindle, the actin ring and septum. Functions upstream of the whole septum formation pathway, including actin ring formation (regulated by late septation genes) and septal material deposition (regulated by early septation genes). Behaves as a 'septum-promoting factor', and could also be involved in inducing other late events of cell division (By similarity).
 
 
 0.664
Y255_ENCCU
Probable serine/threonine-protein kinase ECU02_0550; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    
 0.619
Q8SQM8_ENCCU
PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT.
    
 
 0.616
Q8SS30_ENCCU
ACTIN-LIKE 53kDa PROTEIN; Belongs to the actin family.
   
 
 0.613
ACT_ENCCU
Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
   
 
 0.613
Q8SSB7_ENCCU
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.611
TUB2
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family.
   
 
0.605
Q8SR52_ENCCU
DYNEIN HEAVY CHAIN.
    
 
 0.600
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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