node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A1T5PD76 | GAR1 | A0A1T5PD76 | O96722 | ECU08_1555 protein. | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | 0.999 |
A0A1T5PD76 | NOP1 | A0A1T5PD76 | Q8SR42 | ECU08_1555 protein. | rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...] | 0.760 |
A0A1T5PD76 | Q8SQL0_ENCCU | A0A1T5PD76 | Q8SQL0 | ECU08_1555 protein. | NOP5-LIKE NUCLEOLAR PROTEIN. | 0.853 |
A0A1T5PD76 | Q8SQQ0_ENCCU | A0A1T5PD76 | Q8SQQ0 | ECU08_1555 protein. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.899 |
A0A1T5PD76 | Q8SQW3_ENCCU | A0A1T5PD76 | Q8SQW3 | ECU08_1555 protein. | HIGH MOBILITY GROUP-LIKE NUCLEAR PROTEIN (HMG2). | 0.962 |
A0A1T5PD76 | Q8SRL0_ENCCU | A0A1T5PD76 | Q8SRL0 | ECU08_1555 protein. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.961 |
A0A1T5PD76 | Q8SRW0_ENCCU | A0A1T5PD76 | Q8SRW0 | ECU08_1555 protein. | CENTROMERE/MICROTUBULE BINDING PROTEIN. | 0.999 |
A0A1T5PD76 | Q8SS43_ENCCU | A0A1T5PD76 | Q8SS43 | ECU08_1555 protein. | NUCLEOLAR PROTEIN SIMILAR TO NOP5. | 0.517 |
A0A1T5PD76 | Q8SUF5_ENCCU | A0A1T5PD76 | Q8SUF5 | ECU08_1555 protein. | 60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. | 0.598 |
GAR1 | A0A1T5PD76 | O96722 | A0A1T5PD76 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | ECU08_1555 protein. | 0.999 |
GAR1 | NOP1 | O96722 | Q8SR42 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...] | 0.938 |
GAR1 | Q8SQL0_ENCCU | O96722 | Q8SQL0 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | NOP5-LIKE NUCLEOLAR PROTEIN. | 0.898 |
GAR1 | Q8SQQ0_ENCCU | O96722 | Q8SQQ0 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.804 |
GAR1 | Q8SQW3_ENCCU | O96722 | Q8SQW3 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | HIGH MOBILITY GROUP-LIKE NUCLEAR PROTEIN (HMG2). | 0.998 |
GAR1 | Q8SRL0_ENCCU | O96722 | Q8SRL0 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.890 |
GAR1 | Q8SRW0_ENCCU | O96722 | Q8SRW0 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | CENTROMERE/MICROTUBULE BINDING PROTEIN. | 0.999 |
GAR1 | Q8SS43_ENCCU | O96722 | Q8SS43 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | NUCLEOLAR PROTEIN SIMILAR TO NOP5. | 0.896 |
GAR1 | Q8SUF5_ENCCU | O96722 | Q8SUF5 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | 60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. | 0.737 |
GAR1 | Q8SWN7_ENCCU | O96722 | Q8SWN7 | H/ACA ribonucleoprotein complex subunit GAR1; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA. | Uncharacterized protein. | 0.525 |
NOP1 | A0A1T5PD76 | Q8SR42 | A0A1T5PD76 | rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...] | ECU08_1555 protein. | 0.760 |