STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RVB1RuvB-like protein 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity). (426 aa)    
Predicted Functional Partners:
RVB2
RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
  
0.999
Q8SRZ3_ENCCU
ACTIN-RELATED PROTEIN; Belongs to the actin family.
    
 0.998
Q8SVL2_ENCCU
FAT domain-containing protein.
    
 0.998
Q8SVR4_ENCCU
YL1_C domain-containing protein.
    
 0.987
RPT6
26S proteasome regulatory subunit 8 homolog; Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity); Belongs to the AAA ATPase family.
   
 0.984
Q8SQJ7_ENCCU
GLOBAL TRANSCRIPTIONAL ACTIVATOR (SNF2/RAD54 family).
    
 0.934
Q8SVZ0_ENCCU
Similarity to putative TRANSCRIPTION INITIATION FACTOR TFIIF SMALL SUBUNIT.
    
 0.924
Q8SR51_ENCCU
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.923
Q8SS43_ENCCU
NUCLEOLAR PROTEIN SIMILAR TO NOP5.
   
 
 0.856
Q8SRW0_ENCCU
CENTROMERE/MICROTUBULE BINDING PROTEIN.
   
 0.838
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.