STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y1A1_ENCCUProbable ubiquitin-conjugating enzyme E2 ECU01_1010; Catalyzes the covalent attachment of ubiquitin to other proteins so as to signal them for selective protein degradation. Involved in the formation of multiubiquitin chains. Belongs to the ubiquitin-conjugating enzyme family. (216 aa)    
Predicted Functional Partners:
Q8SWJ6_ENCCU
RING-type domain-containing protein.
   
 0.966
Q8SS94_ENCCU
UBIQUITIN-ACTIVATING ENZYME E1.
  
 0.960
Q8SW66_ENCCU
Skp1 domain-containing protein.
   
 0.918
Q8SRJ4_ENCCU
CULLIN-LIKE PROTEIN; Belongs to the cullin family.
   
 0.888
Q8SWB3_ENCCU
Similarity to monoubiquitin/carboxy-extension protein fusion.
   
 0.873
Q8SRH8_ENCCU
UBIQUITIN/ L40 RIBOSOMAL PROTEIN FUSION.
   
 0.828
UBIQ_ENCCU
Ubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11- [...]
   
 0.828
Q8SSJ1_ENCCU
WD-REPEAT PROTEIN SIMILAR TO CELL DIVISION CONTROL PROTEIN 4 / SEL10 PROTEIN.
    
 0.816
Q8STS6_ENCCU
ThiF domain-containing protein.
  
 0.780
Q8SRK5_ENCCU
UBIQUITIN-LIKE PROTEIN.
   
 0.686
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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