STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHMT-1Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family. (460 aa)    
Predicted Functional Partners:
DHFR-1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
  
 
 0.995
TS-1
Thymidylate synthase 1/2; Belongs to the thymidylate synthase family.
  
 
 0.981
TS-3
Thymidylate synthase 3; Belongs to the thymidylate synthase family.
  
 
 0.981
Q8SVF0_ENCCU
TRANSKETOLASE.
  
 
 0.939
Sua5p
Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
    
 0.913
SYKC_ENCCU
Probable lysine--tRNA ligase, cytoplasmic.
  
  
 0.887
Q8SRX7_ENCCU
SERINE PALMITOYL TRANSFERASE SUBUNIT 2.
  
 
 0.884
Q8SSF4_ENCCU
SERINE PALMITOYLTRANSFERASE SUBUNIT 1.
  
 
 0.884
AMPL_ENCCU
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).
  
 
 0.876
Q8SRZ8_ENCCU
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.875
Your Current Organism:
Encephalitozoon cuniculi
NCBI taxonomy Id: 284813
Other names: E. cuniculi GB-M1, Encephalitozoon cuniculi GB-M1
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