Genes that are sometimes fused into single open reading frames.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFK43224.1
4-oxalocrotonate tautomerase. (76 aa)
Predicted Functional Partners:
SFK43258.1
Hypothetical protein.
0.618
SFJ94538.1
2-keto-4-pentenoate hydratase.
0.504
Your Current Organism:
Pseudovibrio ascidiaceicola
NCBI taxonomy Id: 285279 Other names: DSM 16392, IAM 15084, JCM 21545, KCTC 12308, NBRC 100514, P. ascidiaceicola, Pseudovibrio ascidiaceicola Fukunaga et al. 2006, Pseudovibrio sp. F423, strain F423