SFK87215.1 protein (Pseudovibrio ascidiaceicola)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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[Homology]

Score

SFK87215.1

Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase. (272 aa)

Predicted Functional Partners:

SFK53761.1

0.907

SFK87233.1

0.759

SFK53725.1

0.727

SFL09430.1

0.670

SFK87265.1

0.662

SFK53671.1

0.602

SFK87282.1

0.556

SFK13499.1

0.540

SFK87298.1

0.526

SFK84516.1

0.499

Your Current Organism:

Pseudovibrio ascidiaceicola

NCBI taxonomy Id: 285279
Other names: DSM 16392, IAM 15084, JCM 21545, KCTC 12308, NBRC 100514, P. ascidiaceicola, Pseudovibrio ascidiaceicola Fukunaga et al. 2006, Pseudovibrio sp. F423, strain F423

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFK13499.1	SFK87215.1	SAMN04488518_102319	SAMN04488518_110173	Riboflavin kinase / FMN adenylyltransferase.	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	0.540
SFK53671.1	SFK53725.1	SAMN04488518_106103	SAMN04488518_106106	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	0.999
SFK53671.1	SFK53761.1	SAMN04488518_106103	SAMN04488518_106108	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	0.997
SFK53671.1	SFK87215.1	SAMN04488518_106103	SAMN04488518_110173	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	0.602
SFK53725.1	SFK53671.1	SAMN04488518_106106	SAMN04488518_106103	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	0.999
SFK53725.1	SFK53761.1	SAMN04488518_106106	SAMN04488518_106108	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	0.999
SFK53725.1	SFK87215.1	SAMN04488518_106106	SAMN04488518_110173	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	0.727
SFK53761.1	SFK53671.1	SAMN04488518_106108	SAMN04488518_106103	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	0.997
SFK53761.1	SFK53725.1	SAMN04488518_106108	SAMN04488518_106106	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	0.999
SFK53761.1	SFK87215.1	SAMN04488518_106108	SAMN04488518_110173	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	0.907
SFK84516.1	SFK87215.1	SAMN04488518_11029	SAMN04488518_110173	Lipoic acid synthetase.	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	0.499
SFK84516.1	SFL09430.1	SAMN04488518_11029	SAMN04488518_11685	Lipoic acid synthetase.	Lipoyl(octanoyl) transferase.	0.997
SFK87215.1	SFK13499.1	SAMN04488518_110173	SAMN04488518_102319	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	Riboflavin kinase / FMN adenylyltransferase.	0.540
SFK87215.1	SFK53671.1	SAMN04488518_110173	SAMN04488518_106103	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase.	0.602
SFK87215.1	SFK53725.1	SAMN04488518_110173	SAMN04488518_106106	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL.	0.727
SFK87215.1	SFK53761.1	SAMN04488518_110173	SAMN04488518_106108	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase.	0.907
SFK87215.1	SFK84516.1	SAMN04488518_110173	SAMN04488518_11029	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	Lipoic acid synthetase.	0.499
SFK87215.1	SFK87233.1	SAMN04488518_110173	SAMN04488518_110174	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	TatD DNase family protein.	0.759
SFK87215.1	SFK87265.1	SAMN04488518_110173	SAMN04488518_110176	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	DNA polymerase-3 subunit delta'.	0.662
SFK87215.1	SFK87282.1	SAMN04488518_110173	SAMN04488518_110177	Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase.	Thymidylate kinase.	0.556

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.896

expected number of edges:

10

PPI enrichment p-value:

0.000465

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

10 of 23

2.15

6.76

1.43e-17

GO:0006520

Cellular amino acid metabolic process

11 of 151

1.37

2.55

3.12e-13

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 337

1.02

1.34

4.97e-10

GO:1901566

Organonitrogen compound biosynthetic process

11 of 394

0.96

1.17

2.29e-09

GO:0006139

Nucleobase-containing compound metabolic process

11 of 479

0.87

0.98

1.74e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004812

aminoacyl-tRNA ligase activity

10 of 23

2.15

6.83

7.78e-18

GO:0016874

Ligase activity

11 of 89

1.6

3.75

1.12e-15

GO:0002161

aminoacyl-tRNA editing activity

3 of 7

2.14

2.08

8.04e-05

GO:0000049

tRNA binding

4 of 28

1.67

1.83

5.45e-05

GO:0005524

ATP binding

11 of 311

1.06

1.43

3.21e-10

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1203

0.47

0.39

0.00095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:348

Aminoacyl-tRNA synthetase

5 of 15

2.03

2.81

1.17e-06

CL:350

Aminoacyl-tRNA synthetase

3 of 10

1.99

1.53

0.00094

CL:110

Translation, and Protein export

6 of 137

1.15

1.03

0.00059

CL:355

tRNA synthetases class I (M), and arginyl-tRNA aminoacylation

2 of 5

2.11

0.93

0.0182

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00970

Aminoacyl-tRNA biosynthesis

10 of 31

2.02

6.14

1.69e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

11 of 1008

0.55

0.46

0.00029

GOCC:0005829

Cytosol

8 of 622

0.62

0.44

0.0089

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0030

Aminoacyl-tRNA synthetase

10 of 22

2.17

7.11

1.71e-18

KW-0648

Protein biosynthesis

10 of 49

1.82

4.85

5.53e-16

KW-0436

Ligase

11 of 69

1.71

4.49

3.92e-17

KW-0067

ATP-binding

11 of 252

1.15

1.72

1.58e-11

KW-0820

tRNA-binding

3 of 19

1.71

1.39

0.0011

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13603

Leucyl-tRNA synthetase, Domain 2

3 of 3

2.51

1.94

0.00025

PF08264

Anticodon-binding domain of tRNA ligase

3 of 3

2.51

1.94

0.00025

PF09334

tRNA synthetases class I (M)

3 of 4

2.39

1.92

0.00025

PF00587

tRNA synthetase class II core domain (G, H, P, S and T)

2 of 3

2.33

1.04

0.0122

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00863

Threonyl and Alanyl tRNA synthetase second additional domain

2 of 2

2.51

1.18

0.0070

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