SFF29338.1 protein (Sanguibacter marinus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SFF29338.1

Protein of unknown function. (393 aa)

Predicted Functional Partners:

SFF29300.1

0.966

SFF29357.1

0.962

SFF29374.1

0.962

SFF29320.1

0.903

SFF29265.1

0.778

SFF29247.1

0.775

SFF29428.1

0.643

SFF29286.1

0.610

SFF29409.1

0.571

SFF29394.1

0.540

Your Current Organism:

Sanguibacter marinus

NCBI taxonomy Id: 285351
Other names: CGMCC 1.3457, DSM 19083, JCM 12547, S. marinus, Sanguibacter marinus Huang et al. 2005 emend. Pikuta et al. 2017, Sanguibacter sp. 1-19, strain 1-19

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFF29247.1	SFF29265.1	SAMN04488035_2354	SAMN04488035_2355	Uncharacterized membrane protein YckC, RDD family.	Uncharacterized membrane protein SpoIIM, required for sporulation.	0.946
SFF29247.1	SFF29300.1	SAMN04488035_2354	SAMN04488035_2357	Uncharacterized membrane protein YckC, RDD family.	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	0.785
SFF29247.1	SFF29320.1	SAMN04488035_2354	SAMN04488035_2358	Uncharacterized membrane protein YckC, RDD family.	MoxR-like ATPase.	0.483
SFF29247.1	SFF29338.1	SAMN04488035_2354	SAMN04488035_2359	Uncharacterized membrane protein YckC, RDD family.	Protein of unknown function.	0.775
SFF29247.1	SFF29357.1	SAMN04488035_2354	SAMN04488035_2360	Uncharacterized membrane protein YckC, RDD family.	Protein of unknown function.	0.775
SFF29247.1	SFF29374.1	SAMN04488035_2354	SAMN04488035_2361	Uncharacterized membrane protein YckC, RDD family.	Hypothetical protein.	0.779
SFF29265.1	SFF29247.1	SAMN04488035_2355	SAMN04488035_2354	Uncharacterized membrane protein SpoIIM, required for sporulation.	Uncharacterized membrane protein YckC, RDD family.	0.946
SFF29265.1	SFF29300.1	SAMN04488035_2355	SAMN04488035_2357	Uncharacterized membrane protein SpoIIM, required for sporulation.	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	0.819
SFF29265.1	SFF29320.1	SAMN04488035_2355	SAMN04488035_2358	Uncharacterized membrane protein SpoIIM, required for sporulation.	MoxR-like ATPase.	0.545
SFF29265.1	SFF29338.1	SAMN04488035_2355	SAMN04488035_2359	Uncharacterized membrane protein SpoIIM, required for sporulation.	Protein of unknown function.	0.778
SFF29265.1	SFF29357.1	SAMN04488035_2355	SAMN04488035_2360	Uncharacterized membrane protein SpoIIM, required for sporulation.	Protein of unknown function.	0.778
SFF29265.1	SFF29374.1	SAMN04488035_2355	SAMN04488035_2361	Uncharacterized membrane protein SpoIIM, required for sporulation.	Hypothetical protein.	0.772
SFF29286.1	SFF29300.1	SAMN04488035_2356	SAMN04488035_2357	Hypothetical protein.	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	0.610
SFF29286.1	SFF29320.1	SAMN04488035_2356	SAMN04488035_2358	Hypothetical protein.	MoxR-like ATPase.	0.610
SFF29286.1	SFF29338.1	SAMN04488035_2356	SAMN04488035_2359	Hypothetical protein.	Protein of unknown function.	0.610
SFF29286.1	SFF29357.1	SAMN04488035_2356	SAMN04488035_2360	Hypothetical protein.	Protein of unknown function.	0.610
SFF29286.1	SFF29374.1	SAMN04488035_2356	SAMN04488035_2361	Hypothetical protein.	Hypothetical protein.	0.610
SFF29286.1	SFF29394.1	SAMN04488035_2356	SAMN04488035_2362	Hypothetical protein.	Two-component system, OmpR family, response regulator MtrA.	0.437
SFF29300.1	SFF29247.1	SAMN04488035_2357	SAMN04488035_2354	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Uncharacterized membrane protein YckC, RDD family.	0.785
SFF29300.1	SFF29265.1	SAMN04488035_2357	SAMN04488035_2355	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Uncharacterized membrane protein SpoIIM, required for sporulation.	0.819

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

68

PPI enrichment p-value:

0.235

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007165

Signal transduction

11 of 284

1.28

2.11

1.39e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016772

Transferase activity, transferring phosphorus-containing groups

11 of 299

1.26

2.04

1.41e-11

GO:0000155

Phosphorelay sensor kinase activity

5 of 72

1.53

1.68

5.61e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

11 of 872

0.79

0.82

2.86e-07

GO:0016021

Integral component of membrane

11 of 1024

0.72

0.71

5.52e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3585

Signal transduction histidine kinase-related protein, C-terminal

9 of 35

2.1

6.2

2.39e-16

CL:3573

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

10 of 52

1.97

5.85

3.08e-17

CL:3588

Signal transduction histidine kinase-related protein, C-terminal

8 of 30

2.12

5.71

1.69e-14

CL:3563

Signal transduction histidine kinase-related protein, C-terminal

11 of 68

1.9

5.66

3.39e-18

CL:3590

Mixed, incl. Signal transduction histidine kinase, phosphotransfer (Hpt) domain, and Tll0287-like

5 of 16

2.19

3.83

8.91e-09

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 656

0.91

1.06

1.21e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

11 of 948

0.76

0.75

1.48e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

8 of 155

1.4

2.16

1.84e-08

KW-0418

Kinase

4 of 142

1.14

0.71

0.0151

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005467

Histidine kinase domain

9 of 99

1.65

3.3

3.28e-11

IPR036890

Histidine kinase/HSP90-like ATPase superfamily

9 of 114

1.59

3.06

5.49e-11

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

8 of 92

1.63

3.02

5.54e-10

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

8 of 93

1.63

3.0

5.54e-10

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

8 of 93

1.63

3.0

5.54e-10

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00387

Histidine kinase-like ATPases

9 of 107

1.62

3.32

4.85e-12

SM00388

His Kinase A (phosphoacceptor) domain

8 of 97

1.61

3.08

1.05e-10

SM00448

cheY-homologous receiver domain

9 of 154

1.46

2.63

5.60e-11

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