STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCE70945.1Putative hydrolase of the HAD superfamily. (241 aa)    
Predicted Functional Partners:
SCF15393.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.722
SCF40648.1
Nicotinamide-nucleotide adenylyltransferase, NadR type; Manually curated.
     
 0.695
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.688
SCF02896.1
Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
  
 
 0.629
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.626
SCF15410.1
Riboflavin synthase alpha chain.
   
 
  0.620
SCE70930.1
Permease of the drug/metabolite transporter (DMT) superfamily.
 
     0.619
SCF34593.1
DNA-3-methyladenine glycosylase II.
    
  0.599
SCE63465.1
Putative hydrolase of the HAD superfamily.
  
 
  0.583
SCF43501.1
Zn-dependent protease (includes SpoIVFB); Belongs to the peptidase M50B family.
 
  
  0.528
Your Current Organism:
Micromonospora saelicesensis
NCBI taxonomy Id: 285676
Other names: DSM 44871, JCM 16032, LMG 24056, LMG:24056, M. saelicesensis, Micromonospora saelicesensis Trujillo et al. 2007, Micromonospora sp. Lupac 06, Micromonospora sp. Lupac 07, Micromonospora sp. Lupac 09, strain Lupac 09
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