STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCE74200.1NADPH2:quinone reductase. (326 aa)    
Predicted Functional Partners:
SCE71792.1
Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.844
SCF29468.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.791
SCE74210.1
Antibiotic biosynthesis monooxygenase.
       0.783
SCE74226.1
Transcriptional regulator, TetR family.
       0.773
SCE74185.1
Lysophospholipase L1.
       0.732
SCF33293.1
NADPH:quinone reductase.
  
     0.700
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.608
SCF33253.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.602
SCE71274.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.554
SCF40133.1
Hypothetical protein.
 
    0.547
Your Current Organism:
Micromonospora saelicesensis
NCBI taxonomy Id: 285676
Other names: DSM 44871, JCM 16032, LMG 24056, LMG:24056, M. saelicesensis, Micromonospora saelicesensis Trujillo et al. 2007, Micromonospora sp. Lupac 06, Micromonospora sp. Lupac 07, Micromonospora sp. Lupac 09, strain Lupac 09
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