STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCF04804.1Dihydrofolate reductase. (220 aa)    
Predicted Functional Partners:
SCF04818.1
Uncharacterized conserved protein YndB, AHSA1/START domain.
 
     0.830
SCF04830.1
Transcriptional regulator, ArsR family.
 
     0.808
SCE88323.1
Dihydrofolate reductase.
  
     0.753
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.725
SCF44902.1
Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
     
 0.711
SCF15393.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.686
SCF19305.1
Dihydrofolate reductase.
  
  
  0.685
SCE78693.1
Dihydrofolate reductase.
  
     0.682
SCF43329.1
Dihydrofolate reductase.
  
     0.630
SCF39187.1
Aminomethyltransferase.
     
 0.629
Your Current Organism:
Micromonospora saelicesensis
NCBI taxonomy Id: 285676
Other names: DSM 44871, JCM 16032, LMG 24056, LMG:24056, M. saelicesensis, Micromonospora saelicesensis Trujillo et al. 2007, Micromonospora sp. Lupac 06, Micromonospora sp. Lupac 07, Micromonospora sp. Lupac 09, strain Lupac 09
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