STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_02246Uncharacterized protein. (187 aa)    
Predicted Functional Partners:
PISL3812_07320
Ubiquitin-60S ribosomal protein L40.
    
 0.799
PISL3812_06655
AN1-type domain-containing protein.
   
 0.720
PISL3812_07523
Ubiquitin-like domain-containing protein.
   
 0.720
PISL3812_09343
Polyubiquitin-A.
   
 0.720
PISL3812_01918
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.669
PISL3812_01566
Ubiquitin-activating enzyme E1 C.
    
 0.667
PISL3812_06062
Elongation factor EF-3.
   
   0.664
PISL3812_01176
Ubiquitin-activating enzyme E1; Belongs to the GST superfamily.
    
 0.600
PISL3812_02457
Ubiquitin conjugation factor E4 B.
     
 0.581
PISL3812_07223
Protein pob1.
   
 0.575
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.