STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_02436Lipoate-protein ligase A. (468 aa)    
Predicted Functional Partners:
PISL3812_00271
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.957
PISL3812_00423
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 0.943
PISL3812_06057
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.883
PISL3812_02041
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.859
PISL3812_05355
Peripheral subunit-binding (PSBD) domain-containing protein.
  
 0.859
PISL3812_07826
2-oxoisovalerate dehydrogenase E1 component, alpha subunit.
  
 
 0.833
PISL3812_00614
2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).
  
 0.830
PISL3812_08968
Isochorismatase domain-containing protein.
  
 0.830
PISL3812_08388
Dihydrolipoyl dehydrogenase.
 
 
 0.826
PISL3812_05747
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 
 0.823
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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