STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_03450Uncharacterized protein. (228 aa)    
Predicted Functional Partners:
PISL3812_07404
Vezatin domain-containing protein.
  
 
 0.765
PISL3812_06855
3'-5' exonuclease domain-containing protein.
   
 
 0.707
PISL3812_01924
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 
 0.702
PISL3812_08199
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
    
 0.698
PISL3812_02057
DNA replication ATP-dependent helicase Dna2.
    
 
 0.696
PISL3812_02929
Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
   
 
 0.688
PISL3812_03745
AAA_16 domain-containing protein.
    
 
 0.686
PISL3812_01707
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 
 0.656
PISL3812_03453
Uncharacterized protein.
 
  
   0.654
PISL3812_05085
DNA helicase II / ATP-dependent DNA helicase PcrA.
  
 
 0.641
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.