PISL3812_03589 protein (Talaromyces islandicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PISL3812_03589

Mitochondrial import receptor subunit tom-20. (168 aa)

Predicted Functional Partners:

PISL3812_05405

0.998

PISL3812_00458

0.996

PISL3812_05786

0.994

PISL3812_02509

0.925

PISL3812_01419

0.847

PISL3812_01716

0.847

PISL3812_05102

0.777

PISL3812_03093

0.754

PISL3812_04125

0.754

PISL3812_04801

0.754

Your Current Organism:

Talaromyces islandicus

NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PISL3812_00458	PISL3812_01419	A0A0U1LLA8	A0A0U1LMP6	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.569
PISL3812_00458	PISL3812_02509	A0A0U1LLA8	A0A0U1LSC0	Uncharacterized protein.	Mitochondrial outer membrane protein porin.	0.792
PISL3812_00458	PISL3812_03589	A0A0U1LLA8	A0A0U1LT47	Uncharacterized protein.	Mitochondrial import receptor subunit tom-20.	0.996
PISL3812_00458	PISL3812_05102	A0A0U1LLA8	A0A0U1LXQ7	Uncharacterized protein.	Uncharacterized protein.	0.781
PISL3812_00458	PISL3812_05405	A0A0U1LLA8	A0A0U1LYG9	Uncharacterized protein.	Mitochondrial import receptor subunit tom-70.	0.990
PISL3812_00458	PISL3812_05786	A0A0U1LLA8	A0A0U1LZZ9	Uncharacterized protein.	Mitochondrial import receptor subunit tom-40.	0.998
PISL3812_01419	PISL3812_00458	A0A0U1LMP6	A0A0U1LLA8	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Uncharacterized protein.	0.569
PISL3812_01419	PISL3812_01716	A0A0U1LMP6	A0A0U1LMV2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.762
PISL3812_01419	PISL3812_02509	A0A0U1LMP6	A0A0U1LSC0	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial outer membrane protein porin.	0.821
PISL3812_01419	PISL3812_03093	A0A0U1LMP6	A0A0U1LU25	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Ubiquitin carboxyl-terminal hydrolase.	0.650
PISL3812_01419	PISL3812_03589	A0A0U1LMP6	A0A0U1LT47	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial import receptor subunit tom-20.	0.847
PISL3812_01419	PISL3812_04125	A0A0U1LMP6	A0A0U1LX05	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	USP domain-containing protein.	0.650
PISL3812_01419	PISL3812_04801	A0A0U1LMP6	A0A0U1LYQ3	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Ubiquitin carboxyl-terminal hydrolase 22/27/51; Belongs to the peptidase C19 family.	0.650
PISL3812_01419	PISL3812_05102	A0A0U1LMP6	A0A0U1LXQ7	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Uncharacterized protein.	0.419
PISL3812_01419	PISL3812_05405	A0A0U1LMP6	A0A0U1LYG9	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial import receptor subunit tom-70.	0.783
PISL3812_01419	PISL3812_05786	A0A0U1LMP6	A0A0U1LZZ9	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial import receptor subunit tom-40.	0.465
PISL3812_01716	PISL3812_01419	A0A0U1LMV2	A0A0U1LMP6	USP domain-containing protein; Belongs to the peptidase C19 family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.762
PISL3812_01716	PISL3812_02509	A0A0U1LMV2	A0A0U1LSC0	USP domain-containing protein; Belongs to the peptidase C19 family.	Mitochondrial outer membrane protein porin.	0.665
PISL3812_01716	PISL3812_03589	A0A0U1LMV2	A0A0U1LT47	USP domain-containing protein; Belongs to the peptidase C19 family.	Mitochondrial import receptor subunit tom-20.	0.847
PISL3812_01716	PISL3812_05405	A0A0U1LMV2	A0A0U1LYG9	USP domain-containing protein; Belongs to the peptidase C19 family.	Mitochondrial import receptor subunit tom-70.	0.792

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

47

average node degree:

8.55

avg. local clustering coefficient:

0.968

expected number of edges:

13

PPI enrichment p-value:

1.13e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006470

Protein dephosphorylation

3 of 24

2.07

1.09

0.0087

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004725

Protein tyrosine phosphatase activity

3 of 13

2.34

1.68

0.00070

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:14065

Mixed, incl. Protein autoprocessing, and Cell surface receptor signaling pathway

3 of 11

2.41

1.77

0.00050

CL:2835

Protein phosphatase, and Negative regulation of MAPK cascade

2 of 6

2.5

1.1

0.0098

CL:14067

Cell surface receptor signaling pathway, and FAS1 domain

2 of 5

2.58

1.1

0.0098

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0904

Protein phosphatase

2 of 5

2.58

1.27

0.0048

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003595

Protein-tyrosine phosphatase, catalytic

2 of 3

2.8

1.01

0.0152

IPR000242

Tyrosine-specific protein phosphatase, PTPase domain

2 of 2

2.97

1.01

0.0152

IPR016130

Protein-tyrosine phosphatase, active site

2 of 10

2.28

0.73

0.0463

IPR000387

Tyrosine-specific protein phosphatases domain

2 of 9

2.32

0.73

0.0463

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00194

Protein tyrosine phosphatase, catalytic domain

2 of 2

2.97

1.52

0.0018

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About