STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_03810Uncharacterized protein. (510 aa)    
Predicted Functional Partners:
PISL3812_07610
Putative thiamine biosynthetic bifunctional enzyme.
 
 
 0.996
PISL3812_06087
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
 0.945
PISL3812_04524
Protein NMT1 homolog.
     
 0.928
PISL3812_03811
DNA polymerase.
 
      0.900
PISL3812_07249
Alkaline phosphatase.
    
 0.898
PISL3812_08121
Protein-tyrosine phosphatase.
    
  0.892
PISL3812_07273
Uncharacterized protein.
    
  0.877
thiA
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.877
PISL3812_09532
Pyridoxine kinase.
   
 
 0.831
PISL3812_05919
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
     
 0.810
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.