PISL3812_03274 protein (Talaromyces islandicus)

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Predicted Interactions

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PISL3812_03274

Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1265 aa)

Predicted Functional Partners:

PISL3812_07597

0.819

DNF1

0.806

PISL3812_00466

0.797

PISL3812_09705

0.797

PISL3812_08301

0.702

PISL3812_01592

0.697

PISL3812_02044

0.691

pmrA

0.617

PISL3812_02680

0.617

PISL3812_02897

0.617

Your Current Organism:

Talaromyces islandicus

NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNF1	PISL3812_01592	A0A0U1LSD4	A0A0U1LMJ1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Glycerophosphodiester phosphodiesterase GDE1.	0.541
DNF1	PISL3812_03274	A0A0U1LSD4	A0A0U1LUF6	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.806
DNF1	PISL3812_07597	A0A0U1LSD4	A0A0U1M4P4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	P-type phospholipid transporter.	0.606
PISL3812_00466	PISL3812_01592	A0A0U1LJE7	A0A0U1LMJ1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Glycerophosphodiester phosphodiesterase GDE1.	0.541
PISL3812_00466	PISL3812_03274	A0A0U1LJE7	A0A0U1LUF6	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.797
PISL3812_01592	DNF1	A0A0U1LMJ1	A0A0U1LSD4	Glycerophosphodiester phosphodiesterase GDE1.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.541
PISL3812_01592	PISL3812_00466	A0A0U1LMJ1	A0A0U1LJE7	Glycerophosphodiester phosphodiesterase GDE1.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.541
PISL3812_01592	PISL3812_02680	A0A0U1LMJ1	A0A0U1LQK6	Glycerophosphodiester phosphodiesterase GDE1.	Uncharacterized protein.	0.543
PISL3812_01592	PISL3812_02897	A0A0U1LMJ1	A0A0U1LR63	Glycerophosphodiester phosphodiesterase GDE1.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.583
PISL3812_01592	PISL3812_03274	A0A0U1LMJ1	A0A0U1LUF6	Glycerophosphodiester phosphodiesterase GDE1.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.697
PISL3812_01592	PISL3812_07597	A0A0U1LMJ1	A0A0U1M4P4	Glycerophosphodiester phosphodiesterase GDE1.	P-type phospholipid transporter.	0.541
PISL3812_01592	PISL3812_09705	A0A0U1LMJ1	A0A0U1MBE0	Glycerophosphodiester phosphodiesterase GDE1.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.541
PISL3812_01592	pmrA	A0A0U1LMJ1	A0A0U1LNB2	Glycerophosphodiester phosphodiesterase GDE1.	Ca2+-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.543
PISL3812_02044	PISL3812_03274	A0A0U1LNS1	A0A0U1LUF6	Protein MON2.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.691
PISL3812_02680	PISL3812_01592	A0A0U1LQK6	A0A0U1LMJ1	Uncharacterized protein.	Glycerophosphodiester phosphodiesterase GDE1.	0.543
PISL3812_02680	PISL3812_02897	A0A0U1LQK6	A0A0U1LR63	Uncharacterized protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.536
PISL3812_02680	PISL3812_03274	A0A0U1LQK6	A0A0U1LUF6	Uncharacterized protein.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.617
PISL3812_02897	PISL3812_01592	A0A0U1LR63	A0A0U1LMJ1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Glycerophosphodiester phosphodiesterase GDE1.	0.583
PISL3812_02897	PISL3812_02680	A0A0U1LR63	A0A0U1LQK6	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.536
PISL3812_02897	PISL3812_03274	A0A0U1LR63	A0A0U1LUF6	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.617

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Network Stats

number of nodes:

9

number of edges:

36

average node degree:

8

avg. local clustering coefficient:

1

expected number of edges:

8

PPI enrichment p-value:

8.16e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007035

Vacuolar acidification

2 of 19

2.55

1.22

0.0255

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

3 of 22

2.66

3.31

3.64e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016471

Vacuolar proton-transporting V-type ATPase complex

3 of 21

2.68

3.55

1.67e-05

GO:0000220

Vacuolar proton-transporting V-type ATPase, V0 domain

2 of 12

2.75

2.29

0.0010

GO:0000329

Fungal-type vacuole membrane

2 of 73

1.96

1.33

0.0128

GO:0031090

Organelle membrane

4 of 973

1.14

1.0

0.0026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6446

Proton-transporting V-type ATPase, V1 domain, and V-ATPase proteolipid subunit C, eukaryotic

3 of 12

2.93

3.8

9.91e-06

CL:6449

Proton-transporting V-type ATPase, V1 domain

2 of 7

2.98

2.36

0.00088

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

aalt04145

Phagosome

3 of 33

2.49

3.64

8.55e-06

aalt00190

Oxidative phosphorylation

3 of 73

2.14

2.92

4.20e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-917977

Transferrin endocytosis and recycling

3 of 22

2.66

3.47

2.14e-05

MAP-77387

Insulin receptor recycling

3 of 22

2.66

3.47

2.14e-05

MAP-74752

Signaling by Insulin receptor

3 of 24

2.62

3.45

2.14e-05

MAP-1222556

ROS and RNS production in phagocytes

3 of 24

2.62

3.45

2.14e-05

MAP-9639288

Amino acids regulate mTORC1

3 of 42

2.38

3.25

2.64e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033176

Proton-transporting V-type ATPase complex

2 of 16

2.62

1.52

0.0102

GOCC:0005773

Vacuole

3 of 187

1.73

1.3

0.0102

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

3 of 15

2.83

4.28

1.96e-06

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