STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_05828tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG. (686 aa)    
Predicted Functional Partners:
PISL3812_05802
tRNA modification GTPase MnmE.
 0.986
PISL3812_05811
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
 
      0.900
PISL3812_02431
Uncharacterized protein.
  
  
 0.545
PISL3812_04362
Mitochondrial inner membrane protein OXA1.
  
  
 0.545
PISL3812_04297
Cysteinyl-tRNA synthetase.
  
  
 0.534
PISL3812_02441
Methionyl-tRNA formyltransferase.
  
  
 0.523
PISL3812_03243
Pumilio homolog 3.
    
   0.505
PISL3812_07551
tRNA pseudouridine synthase A.
      
 0.449
uba4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
      
 0.447
PISL3812_07404
Vezatin domain-containing protein.
  
  
 0.444
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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