STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PISL3812_08464Pterin-binding domain-containing protein. (480 aa)    
Predicted Functional Partners:
PISL3812_02560
Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.983
PISL3812_04409
GTP cyclohydrolase I.
 
 
 0.977
PISL3812_05064
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
 
 
 0.953
PISL3812_05404
Uncharacterized protein.
     
 0.918
PISL3812_07173
Folylpolyglutamate synthase.
  
 
 0.915
FPGS
Folylpolyglutamate synthase.
  
 
 0.915
PISL3812_03236
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.851
PISL3812_05243
annotation not available
  
 
 0.837
trpC
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.829
PISL3812_04787
Anthranilate synthase component I.
  
 
 0.801
Your Current Organism:
Talaromyces islandicus
NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.