PISL3812_09317 protein (Talaromyces islandicus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PISL3812_09317

Uncharacterized protein. (187 aa)

Predicted Functional Partners:

PISL3812_05434

0.965

PISL3812_07756

0.961

PISL3812_08730

0.949

PISL3812_01079

0.942

PISL3812_02051

0.942

PISL3812_04832

0.941

PISL3812_07569

0.941

PISL3812_04548

0.939

PISL3812_06477

0.936

PISL3812_00903

0.934

Your Current Organism:

Talaromyces islandicus

NCBI taxonomy Id: 28573
Other names: ATCC 10127, CBS 338.48, IMI 040042, MUCL 31324, Penicillium islandicum, T. islandicus, Talaromyces islandicus (Sopp) Samson, Yilmaz, Frisvad & Seifert 2012

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PISL3812_00903	PISL3812_01079	A0A0U1LMM7	A0A0U1LL13	Uncharacterized protein.	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	0.683
PISL3812_00903	PISL3812_02051	A0A0U1LMM7	A0A0U1LR28	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.905
PISL3812_00903	PISL3812_04548	A0A0U1LMM7	A0A0U1LY23	Uncharacterized protein.	Anaphase-promoting complex subunit CDC16.	0.999
PISL3812_00903	PISL3812_04832	A0A0U1LMM7	A0A0U1LYJ5	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.	0.995
PISL3812_00903	PISL3812_05434	A0A0U1LMM7	A0A0U1LYJ9	Uncharacterized protein.	Mitotic spindle checkpoint component mad2.	0.994
PISL3812_00903	PISL3812_06477	A0A0U1LMM7	A0A0U1M378	Uncharacterized protein.	Anaphase-promoting complex subunit 4.	0.999
PISL3812_00903	PISL3812_07569	A0A0U1LMM7	A0A0U1M4S0	Uncharacterized protein.	Protein bimA.	0.999
PISL3812_00903	PISL3812_07756	A0A0U1LMM7	A0A0U1M6M1	Uncharacterized protein.	Checkpoint serine/threonine-protein kinase.	0.987
PISL3812_00903	PISL3812_08730	A0A0U1LMM7	A0A0U1M9P0	Uncharacterized protein.	Serine/threonine protein kinase, putative.	0.912
PISL3812_00903	PISL3812_09317	A0A0U1LMM7	A0A0U1MB78	Uncharacterized protein.	Uncharacterized protein.	0.934
PISL3812_01079	PISL3812_00903	A0A0U1LL13	A0A0U1LMM7	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Uncharacterized protein.	0.683
PISL3812_01079	PISL3812_04548	A0A0U1LL13	A0A0U1LY23	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Anaphase-promoting complex subunit CDC16.	0.770
PISL3812_01079	PISL3812_04832	A0A0U1LL13	A0A0U1LYJ5	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.	0.867
PISL3812_01079	PISL3812_05434	A0A0U1LL13	A0A0U1LYJ9	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Mitotic spindle checkpoint component mad2.	0.905
PISL3812_01079	PISL3812_06477	A0A0U1LL13	A0A0U1M378	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Anaphase-promoting complex subunit 4.	0.859
PISL3812_01079	PISL3812_07569	A0A0U1LL13	A0A0U1M4S0	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Protein bimA.	0.937
PISL3812_01079	PISL3812_07756	A0A0U1LL13	A0A0U1M6M1	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Checkpoint serine/threonine-protein kinase.	0.907
PISL3812_01079	PISL3812_08730	A0A0U1LL13	A0A0U1M9P0	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Serine/threonine protein kinase, putative.	0.972
PISL3812_01079	PISL3812_09317	A0A0U1LL13	A0A0U1MB78	G2/mitotic-specific cyclin-4; Belongs to the cyclin family.	Uncharacterized protein.	0.942
PISL3812_02051	PISL3812_00903	A0A0U1LR28	A0A0U1LMM7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.905

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.826

expected number of edges:

11

PPI enrichment p-value:

0.00675

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019333

Denitrification pathway

3 of 3

2.6

2.03

0.00030

GO:0042128

Nitrate assimilation

3 of 5

2.38

1.92

0.00041

GO:0006825

Copper ion transport

2 of 2

2.6

1.24

0.0075

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050421

Nitrite reductase (NO-forming) activity

3 of 3

2.6

2.19

0.00016

GO:0005507

Copper ion binding

3 of 9

2.12

1.87

0.00036

GO:0046914

Transition metal ion binding

4 of 116

1.14

0.75

0.0124

GO:0046872

Metal ion binding

7 of 448

0.79

0.62

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3523

Mixed, incl. Heavy-metal-associated domain, and Copper ion binding

5 of 17

2.07

3.11

5.70e-07

CL:3525

Mixed, incl. Copper ion binding, and P-type ATPase, subfamily IB

4 of 10

2.2

2.81

5.18e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042597

Periplasmic space

5 of 150

1.12

0.85

0.0045

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF07732

Multicopper oxidase

3 of 3

2.6

2.25

0.00012

PF00394

Multicopper oxidase

3 of 3

2.6

2.25

0.00012

PF00403

Heavy-metal-associated domain

2 of 4

2.3

1.05

0.0148

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045087

Multicopper oxidase

3 of 3

2.6

2.02

0.00032

IPR033138

Multicopper oxidases, conserved site

3 of 3

2.6

2.02

0.00032

IPR011707

Multicopper oxidase, N-terminal

3 of 3

2.6

2.02

0.00032

IPR011706

Multicopper oxidase, C-terminal

3 of 3

2.6

2.02

0.00032

IPR002355

Multicopper oxidase, copper-binding site

3 of 3

2.6

2.02

0.00032

(more ...)

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