STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SeMB42_g04119GRIP domain-containing protein. (1319 aa)    
Predicted Functional Partners:
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
    
 0.941
SeMB42_g02835
Uncharacterized protein.
   
 0.905
SeMB42_g05037
Adenylate kinase.
   
 0.878
SENL776
Adenine phosphoribosyltransferase.
  
 
 0.866
SeMB42_g01824
Inorganic diphosphatase.
   
 0.827
SeMB42_g06626
CASP_C domain-containing protein.
    
 
 0.819
SeMB42_g04151
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
    
  0.809
SeMB42_g04414
DNA-directed RNA polymerase.
  
  
 0.803
SeMB42_g01896
Uncharacterized protein.
    
 0.800
SeMB42_g00571
ANK_REP_REGION domain-containing protein.
    
 0.800
Your Current Organism:
Synchytrium endobioticum
NCBI taxonomy Id: 286115
Other names: S. endobioticum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.