STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SeMB42_g04298S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (300 aa)    
Predicted Functional Partners:
SENL776
Adenine phosphoribosyltransferase.
 
 
 0.981
SPE3
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 
 0.860
MRI1-2
S-methyl-5-thioribose-1-phosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family.
  
 
 0.851
SeMB42_g06384
PNP_UDP_1 domain-containing protein.
    
 0.826
SENL437
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
    
 0.791
SeMB42_g01993
Uncharacterized protein.
  
 
 0.790
SeMB42_g06517
Uncharacterized protein.
  
 
 0.778
SeMB42_g02236
Aminotran_1_2 domain-containing protein.
    
 0.762
SENL699
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
    
 0.744
SeMB42_g01776
ENDO3c domain-containing protein.
    
  0.738
Your Current Organism:
Synchytrium endobioticum
NCBI taxonomy Id: 286115
Other names: S. endobioticum
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