STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SeMB42_g04117Hist_deacetyl domain-containing protein. (483 aa)    
Predicted Functional Partners:
SeMB42_g02408
Response regulatory domain-containing protein.
   
 0.978
SeMB42_g03481
Uncharacterized protein.
    
 0.977
SeMB42_g05890
HDAC_interact domain-containing protein.
    
 0.840
SeMB42_g01212
HDAC_interact domain-containing protein.
    
 0.840
SeMB42_g03397
WD_REPEATS_REGION domain-containing protein.
   
 0.835
SeMB42_g03719
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
  
 
 0.834
SeMB42_g04433
WD_REPEATS_REGION domain-containing protein.
   
 0.831
SeMB42_g00223
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
  
 
 0.827
SeMB42_g01113
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.825
SeMB42_g05153
SWIRM domain-containing protein.
    
 0.821
Your Current Organism:
Synchytrium endobioticum
NCBI taxonomy Id: 286115
Other names: S. endobioticum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.