close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP2Matrix metallopeptidase 2. (669 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.981
THBS1
Thrombospondin 1.
   
 0.957
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 0.954
MMP1
Interstitial collagenase-like.
   
 
0.947
EDN1
Endothelin 1.
     
 0.947
MMP14
Matrix metallopeptidase 14.
   
0.945
HBEGF
Heparin binding EGF like growth factor.
    
 0.941
CYBB
Cytochrome b-245 heavy chain.
   
 
 0.941
MMP9
Matrix metallopeptidase 9.
  
 
0.941
NCF4
Neutrophil cytosolic factor 4.
   
 
 0.939
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.