Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO4R-spondin 4. (232 aa)    
Predicted Functional Partners:
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.990
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.979
RNF43
Ring finger protein 43.
    
 0.941
ZNRF3
Zinc and ring finger 3.
    
 0.932
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.920
RSPO3
R-spondin 3.
     
 0.891
RSPO2
R-spondin 2.
     
  0.848
RSPO1
R-spondin 1.
     
  0.813
UNC5A
Unc-5 netrin receptor A.
      
 0.747
RXFP1
Relaxin family peptide receptor 1.
   
 0.675
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.