close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (643 aa)    
Predicted Functional Partners:
PLXNC1
Plexin C1.
    
 0.998
ITGB1
Integrin subunit beta 1.
     
 0.964
PLXNB3
Plexin B3.
    
 0.781
PLXND1
Plexin D1.
    
 0.769
PLXNA2
Plexin A2.
    
0.750
PLXNA1
Plexin A1.
    
 0.736
PLXNA4
Plexin A4.
    
 0.734
PLXNA3
Plexin A3.
    
 0.731
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.691
MST1R
Macrophage stimulating 1 receptor.
    
 0.691
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.