Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (643 aa)    
Predicted Functional Partners:
PLXNC1
Plexin C1.
    
 0.997
ITGB1
Integrin subunit beta 1.
    
 0.937
PLXND1
Plexin D1.
    
 0.872
PLXNA1
Plexin A1.
    
 0.861
PLXNA3
Plexin A3.
    
 0.818
PLXNA2
Plexin A2.
    
 0.818
PLXNA4
Plexin A4.
    
 0.818
FAM185A
Family with sequence similarity 185 member A.
    
   0.814
LOC112670362
Negative regulator of P-body association-like.
    
   0.715
ITGB2
Integrin subunit beta 2.
    
 0.714
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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