Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPGDSHematopoietic prostaglandin D synthase. (199 aa)    
Predicted Functional Partners:
PTGDS
Prostaglandin D2 synthase.
   
 
 0.955
PRDX6
Peroxiredoxin 6.
   
 0.938
PTGIS
Prostaglandin I2 synthase.
   
 
 0.929
GSTO1
Glutathione S-transferase omega 1.
   
 0.928
GSR
Glutathione-disulfide reductase.
   
 
 0.927
PTGS1
Prostaglandin-endoperoxide synthase 1.
     
 0.924
GSS
Glutathione synthetase.
   
 0.920
MGST2
Microsomal glutathione S-transferase 2.
     
 0.918
MGST1
Microsomal glutathione S-transferase 1.
   
 
 0.917
EPHX1
Epoxide hydrolase 1.
   
 
 0.915
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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