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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHSNHS actin remodeling regulator. (1518 aa)    
Predicted Functional Partners:
MIB1
Mindbomb E3 ubiquitin protein ligase 1.
   
 0.780
HSF1
Heat shock transcription factor 1.
    
 0.719
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.590
NCKAP1
NCK associated protein 1.
    
  0.588
ARID4A
AT-rich interaction domain 4A.
    
 0.588
ARID4B
AT-rich interaction domain 4B.
    
 0.588
RAC2
Rac family small GTPase 2.
    
  0.582
LOC112674186
Neuroendocrine secretory protein 55.
   
 0.565
RAC3
Rac family small GTPase 3.
    
  0.549
RAC1
Rac family small GTPase 1.
    
  0.549
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.