Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP28Ubiquitin specific peptidase 28. (1131 aa)    
Predicted Functional Partners:
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 0.981
TP53BP1
Tumor protein p53 binding protein 1.
   
 
 0.927
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.902
LOC112647137
Ubiquitin.
   
 0.873
TRAF5
TNF receptor associated factor 5.
    
 0.846
TP53
Tumor protein p53.
    
 0.808
TRAF6
TNF receptor associated factor 6.
    
 0.807
ENSCAFP00020011461
annotation not available
    
  0.787
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.787
ENSCAFP00020015425
annotation not available
    
  0.787
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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