Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COTL1Coactosin like F-actin binding protein 1. (142 aa)    
Predicted Functional Partners:
ALOX5
Arachidonate 5-lipoxygenase.
    
 
 0.972
ALOX12B
Arachidonate 12-lipoxygenase, 12R type.
    
 
 0.876
ALOX15B
Arachidonate 15-lipoxygenase type B.
    
 
 0.876
CAPZB
Capping actin protein of muscle Z-line subunit beta.
   
 0.764
ACTR2
Actin related protein 2.
   
 
 0.688
LCP1
Lymphocyte cytosolic protein 1.
   
 
 0.609
HIP1
Huntingtin interacting protein 1.
    
 
 0.603
HIP1R
Huntingtin interacting protein 1 related.
    
 
 0.603
WAS
WASP actin nucleation promoting factor.
   
 
 0.595
WASL
WASP like actin nucleation promoting factor.
   
 
 0.595
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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