Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXL1Forkhead box L1. (356 aa)    
Predicted Functional Partners:
RSPO3
R-spondin 3.
     
 0.695
PPARA
Peroxisome proliferator activated receptor alpha.
    
 0.575
E2F1
E2F transcription factor 1.
   
 
 0.568
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.551
IRX4
Iroquois homeobox 4.
    
 
 0.544
SUOX
Sulfite oxidase.
     
  0.525
TBPL2
TATA-box binding protein like 2.
    
 0.520
TBP
TATA-box binding protein.
    
 0.520
TMEM200A
Transmembrane protein 200A.
      
 0.519
WNT2B
Wnt family member 2B.
      
 0.513
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
Server load: low (28%) [HD]