Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PITRM1Pitrilysin metallopeptidase 1. (940 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 
 0.866
GRPEL1
GrpE like 1, mitochondrial.
   
 
 0.827
PDHA1
Pyruvate dehydrogenase E1 alpha 1 subunit.
   
 
 0.819
PDHB
Pyruvate dehydrogenase E1 beta subunit.
    
   0.814
SUCLG2
succinate-CoA ligase GDP-forming beta subunit.
   
   0.809
DLD
Dihydrolipoamide dehydrogenase.
    
 
 0.781
COQ2
Coenzyme Q2, polyprenyltransferase.
     
 0.762
XPNPEP2
X-prolyl aminopeptidase 2.
   
 
 0.740
XPNPEP1
X-prolyl aminopeptidase 1.
   
 
 0.740
PDHX
Pyruvate dehydrogenase complex component X.
    
 
 0.728
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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