Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 0.990
ADIPOR2
Adiponectin receptor 2.
    
 0.940
ADIPOR1
Adiponectin receptor 1.
    
 0.940
PAQR6
Progestin and adipoQ receptor family member 6.
    
 0.935
PAQR5
Progestin and adipoQ receptor family member 5.
    
 0.935
PAQR9
Progestin and adipoQ receptor family member 9.
    
 0.935
PAQR3
Progestin and adipoQ receptor family member 3.
    
 0.935
PAQR8
Progestin and adipoQ receptor family member 8.
    
 0.935
PAQR7
Progestin and adipoQ receptor family member 7.
    
 0.935
PAQR4
Progestin and adipoQ receptor family member 4.
    
 0.935
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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