Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
PTS6-pyruvoyltetrahydropterin synthase. (153 aa)    
Predicted Functional Partners:
SPR
Sepiapterin reductase.
   
 
 0.959
GCH1
GTP cyclohydrolase 1.
  
 
 0.955
LOC112658979
Estradiol 17 beta-dehydrogenase 5-like.
     
 0.881
ALPL
Alkaline phosphatase, biomineralization associated.
     
  0.881
ALPI
Alkaline phosphatase, intestinal.
     
  0.881
GCHFR
GTP cyclohydrolase I feedback regulator.
     
 0.859
PRKG2
Protein kinase cGMP-dependent 2.
   
  0.827
ENSCAFP00020021121
annotation not available
     
 0.774
AKR1B1
Aldo-keto reductase family 1 member B.
     
 0.774
PTPRA
Protein tyrosine phosphatase receptor type A.
    
 
 0.687
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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