STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GDF15Growth differentiation factor 15. (307 aa)    
Predicted Functional Partners:
TGFBR2
Transforming growth factor beta receptor 2.
    
 0.953
RET
Ret proto-oncogene.
    
 
 0.877
GFRAL
GDNF family receptor alpha like.
   
 
 0.772
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
    
 0.540
LRRC25
Leucine rich repeat containing 25.
  
 
 0.521
FGF21
Fibroblast growth factor 21.
   
  
 0.499
ATF3
Activating transcription factor 3.
   
  
 0.490
RBM42
RNA binding motif protein 42.
      
 0.461
CHPF
Chondroitin polymerizing factor.
      
 0.450
CDKN1A
Cyclin dependent kinase inhibitor 1A.
      
 0.440
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.