STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHCR2424-dehydrocholesterol reductase. (516 aa)    
Predicted Functional Partners:
CYP51A1
Lanosterol 14-alpha demethylase.
   
 0.992
DHCR7
7-dehydrocholesterol reductase.
   
 0.990
SC5D
sterol-C5-desaturase.
   
 
 0.985
LSS
Lanosterol synthase.
   
 
 0.982
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.971
TM7SF2
Transmembrane 7 superfamily member 2.
   
 0.969
LBR
Lamin B receptor.
   
 0.962
CYP7A1
Cholesterol 7-alpha-monooxygenase.
   
 0.954
SOAT2
Sterol O-acyltransferase 2.
     
 0.951
SOAT1
Sterol O-acyltransferase 1.
     
 0.947
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.