STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MC4RMelanocortin 4 receptor. (321 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin.
    
 0.996
NPY
Neuropeptide Y.
    
 0.929
MC2R
Melanocortin 2 receptor.
  
 
0.918
MC3R
Melanocortin 3 receptor.
   
 
0.902
ENSCAFP00020028093
annotation not available
    
 0.829
GNAS
GNAS complex locus.
    
 0.829
GNAL
G protein subunit alpha L.
    
 0.829
AGRP
Agouti related neuropeptide.
    
 
 0.795
GHRL
Ghrelin and obestatin prepropeptide.
    
 0.792
CCK
Cholecystokinin.
    
 0.787
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.