STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT4Sirtuin 4. (312 aa)    
Predicted Functional Partners:
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.964
NADSYN1
NAD synthetase 1.
    
 0.953
PNP
Purine nucleoside phosphorylase.
    
 0.945
NUDT12
Nudix hydrolase 12.
    
 0.944
CD38
CD38 molecule.
     
 0.942
NNT
Nicotinamide nucleotide transhydrogenase.
   
 
 0.940
SIRT3
Sirtuin 3.
  
 
0.934
NADK
NAD kinase.
  
 
 0.928
SIRT7
Sirtuin 7.
  
  
0.925
BST1
Bone marrow stromal cell antigen 1.
     
 0.924
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.