STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HGFHepatocyte growth factor. (689 aa)    
Predicted Functional Partners:
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.998
EGF
Epidermal growth factor.
     
 0.975
IGF1
Insulin like growth factor 1.
     
 0.971
EGFR
Epidermal growth factor receptor.
    
 0.958
VEGFC
Vascular endothelial growth factor C.
     
 0.954
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.952
PGF
Placental growth factor.
     
 0.939
FGFR4
Fibroblast growth factor receptor 4.
    
 0.939
PDGFB
Platelet derived growth factor subunit B.
     
 0.938
IGF1R
Insulin like growth factor 1 receptor.
    
 0.935
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.