STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CH25HCholesterol 25-hydroxylase. (289 aa)    
Predicted Functional Partners:
CYP7B1
25-hydroxycholesterol 7-alpha-hydroxylase.
   
 0.995
CYP7A1
Cholesterol 7-alpha-monooxygenase.
   
 0.984
CYP46A1
Cholesterol 24-hydroxylase.
   
 0.979
CYP27A1
Sterol 26-hydroxylase, mitochondrial.
   
 0.969
DHCR7
7-dehydrocholesterol reductase.
   
 0.945
DHCR24
24-dehydrocholesterol reductase.
   
 
 0.943
SC5D
sterol-C5-desaturase.
   
0.940
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7.
   
 0.940
CYP51A1
Lanosterol 14-alpha demethylase.
   
 0.930
LIPA
Lipase A, lysosomal acid type.
     
 0.930
Your Current Organism:
Canis lupus dingo
NCBI taxonomy Id: 286419
Other names: C. lupus dingo, Canis familiaris dingo, dingo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.