node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1222 | DR97_1225 | DR97_1222 | DR97_1225 | Hypothetical protein; Uncharacterized protein | annotation not available | 0.529 |
DR97_1222 | sdhE | DR97_1222 | DR97_1224 | Hypothetical protein; Uncharacterized protein | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.862 |
DR97_1225 | DR97_1222 | DR97_1225 | DR97_1222 | annotation not available | Hypothetical protein; Uncharacterized protein | 0.529 |
DR97_1225 | nfuA | DR97_1225 | DR97_30 | annotation not available | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | 0.779 |
DR97_1225 | sdhE | DR97_1225 | DR97_1224 | annotation not available | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.624 |
DR97_4851 | nfuA | DR97_4851 | DR97_30 | Uncharacterized protein; DUF1315 domain-containing protein | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | 0.619 |
DR97_4851 | sdhD | DR97_4851 | DR97_307 | Uncharacterized protein; DUF1315 domain-containing protein | Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) | 0.699 |
DR97_4851 | sdhE | DR97_4851 | DR97_1224 | Uncharacterized protein; DUF1315 domain-containing protein | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.618 |
DR97_4851 | topA | DR97_4851 | DR97_4926 | Uncharacterized protein; DUF1315 domain-containing protein | Dna topoisomerase i; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.610 |
DR97_4851 | zipA | DR97_4851 | DR97_408 | Uncharacterized protein; DUF1315 domain-containing protein | Cell division protein zipa; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins | 0.543 |
nfuA | DR97_1225 | DR97_30 | DR97_1225 | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | annotation not available | 0.779 |
nfuA | DR97_4851 | DR97_30 | DR97_4851 | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | Uncharacterized protein; DUF1315 domain-containing protein | 0.619 |
nfuA | sdhE | DR97_30 | DR97_1224 | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.754 |
nfuA | topA | DR97_30 | DR97_4926 | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | Dna topoisomerase i; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.735 |
nfuA | zipA | DR97_30 | DR97_408 | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | Cell division protein zipa; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins | 0.511 |
rplP | sdhE | DR97_3655 | DR97_1224 | Large subunit ribosomal protein l16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.629 |
sdhA | sdhC | DR97_306 | DR97_308 | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | 0.999 |
sdhA | sdhD | DR97_306 | DR97_307 | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) | 0.999 |
sdhA | sdhE | DR97_306 | DR97_1224 | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Flavinator of succinate dehydrogenase family protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.835 |
sdhC | sdhA | DR97_308 | DR97_306 | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.999 |