pagL protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pagL

Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family (173 aa)

Predicted Functional Partners:

phoP

0.857

lpxO1

0.853

oprD3

0.779

phoQ

0.766

lpxO2

0.750

wapQ

0.704

oprF

0.697

rpmF

0.682

DR97_2347

0.679

DR97_4428

0.672

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_2347	DR97_4428	DR97_2347	DR97_4428	Metal ABC transporter ATPase	Leucyl-tRNA synthetase	0.776
DR97_2347	pagL	DR97_2347	DR97_1970	Metal ABC transporter ATPase	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.679
DR97_2347	wapQ	DR97_2347	DR97_2362	Metal ABC transporter ATPase	annotation not available	0.519
DR97_4428	DR97_2347	DR97_4428	DR97_2347	Leucyl-tRNA synthetase	Metal ABC transporter ATPase	0.776
DR97_4428	pagL	DR97_4428	DR97_1970	Leucyl-tRNA synthetase	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.672
DR97_4428	wapQ	DR97_4428	DR97_2362	Leucyl-tRNA synthetase	annotation not available	0.597
lpxO1	pagL	DR97_1691	DR97_1970	annotation not available	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.853
lpxO1	phoP	DR97_1691	DR97_755	annotation not available	annotation not available	0.715
lpxO1	phoQ	DR97_1691	DR97_754	annotation not available	annotation not available	0.552
lpxO2	pagL	DR97_1003	DR97_1970	annotation not available	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.750
lpxO2	phoP	DR97_1003	DR97_755	annotation not available	annotation not available	0.550
lpxO2	phoQ	DR97_1003	DR97_754	annotation not available	annotation not available	0.456
oprD3	oprF	DR97_5193	DR97_109	annotation not available	annotation not available	0.759
oprD3	pagL	DR97_5193	DR97_1970	annotation not available	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.779
oprD3	wapQ	DR97_5193	DR97_2362	annotation not available	annotation not available	0.547
oprF	oprD3	DR97_109	DR97_5193	annotation not available	annotation not available	0.759
oprF	pagL	DR97_109	DR97_1970	annotation not available	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	0.697
oprF	rpmF	DR97_109	DR97_4969	annotation not available	rpmF_bact: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family	0.526
pagL	DR97_2347	DR97_1970	DR97_2347	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	Metal ABC transporter ATPase	0.679
pagL	DR97_4428	DR97_1970	DR97_4428	Lipid A deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family	Leucyl-tRNA synthetase	0.672

page 1 of 3

Network

Neighborhood

Experiments

Fusion

Textmining

Cooccurrence

Databases

Coexpression

© STRING Consortium 2020

Credits

Access

Info

About