STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
lldDL-lactate dehydrogenase (cytochrome); Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain (381 aa)    
Predicted Functional Partners:
glcA
Glycolate permease glca; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate
 
  
 0.992
DR97_2116
D-lactate dehydrogenase; Ferredoxin; FAD linked oxidase, C-terminal domain protein
  
 
 0.973
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
    
 0.958
ldhA
D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.927
poxB
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family
  
 
 0.927
DR97_5745
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family
  
 
 0.927
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
    
 0.922
pykA
Belongs to the pyruvate kinase family
   
 
 0.917
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family
     
 0.917
PdhB
Putative pyruvate dehydrogenase e1 component beta chain; Pyruvate dehydrogenase E1 component subunit beta; Transketolase, C-terminal domain protein
     
 0.916
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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