STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine (636 aa)    
Predicted Functional Partners:
aguA
Agmatine deiminase; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine
 
  
 0.992
speE1
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
    
 0.948
astA
Arginine/ornithine succinyltransferase aii subunit; arg_catab_AstA: arginine N-succinyltransferase
     
 0.946
aguB
N-carbamoylputrescine amidohydrolase; agmatine_aguB: N-carbamoylputrescine amidase
 
   
 0.919
aruH
Cys/met metabolism plp-dependent enzyme family protein; Catalyzes the conversion of L-arginine into 2-ketoarginine via transamination. L-arginine is the best substrate, but it can also use L-lysine, L-methionine, L-leucine, ornithine and L-glutamine, which indicates that it may have a broader physiological function in amino acid catabolism
    
  0.905
aruF
Arginine/ornithine succinyltransferase, alpha subunit; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. Also acts on L-ornithine
     
  0.900
speC
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family
     
 0.884
arcA
arcA: arginine deiminase
     
 0.876
ldcA
Beta-eliminating lyase family protein; Plays an essential role in lysine utilization by acting as a lysine decarboxylase
     
 0.865
argH
argH: argininosuccinate lyase
   
 
 0.863
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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