The upcoming version of STRING is available for preview: it includes new data, new enrichment categories (e.g. diseases and tissues) and covers 14000 fully sequenced genomes.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilM
pilM: type IV pilus assembly PilM family protein (354 aa)
Predicted Functional Partners:
pilN
annotation not available
0.995
pilO
annotation not available
0.994
DR97_2396
annotation not available
0.991
pilQ
IV_pilus_PilQ: type IV pilus secretin PilQ family protein
0.990
DR97_2973
annotation not available
0.882
hxcQ
type_II_gspD: type II secretion system protein D
0.847
pilE
Type 4 fimbrial biogenesis protein PilE; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein
0.791
pilC
annotation not available
0.784
pilZ
annotation not available
0.782
mrcA
PBP_1a_fam: penicillin-binding , 1A family protein
STRING Data Update
